Endocrine Abstracts

A 58-year old female with long standing type 1 diabetes and treated hypothyroidism presented to casualty with a 1-day history of vomiting and breathlessness. Clinically she was dehydrated with a depressed conscious level (GCS=12). Initial investigations confirmed diabetic ketoacidosis (pH=6.8, bicarbonate=4.7 mmol/l, urinary ketones=4+, blood glucose=54.6 mmol/l) and acute renal failure, likely to be secondary to pneumonia as there was consolidation on her CXR and a raised WCC...

Forty-seven years old lady presented to another hospital with symptoms of diarrhea and sleep disturbance. She was found to have abnormal thyroid function tests (TFTs) with fT4 44 fT3 12 and TSH 3.4. She had no goiter or thyroid eye signs. Thyroid ultrasound showed a multinodular goiter and an uptake scan was consistent with thyrotoxicosis.She was commenced on carbimazole and in 2001 radio-iodine was administered for a presumed diagn...

Background: Differentiated thyroid cancers are reported to present with synchronous distant metastases in 1–9% of cases. The most common single sites of synchronous metastases are lung (45%) and bone (39%) with dual site involvement (12%). Other single sites of metastases are rare (4%). Pleural metastases are very unusual, accounting for < 0.6% of cases.Case: A 55-year-old male smoker presented with cough, weight loss and thoracic back pain. Exa...